Dose of vitamin K in emergency reversal of warfarin anticoagulation
نویسندگان
چکیده
منابع مشابه
Prothrombin complex concentrates in warfarin anticoagulation reversal
Anticoagulation is very effective for primary and secondary prevention of thromboembolic events. However, questions persist about the risks and management of over-anticoagulation. The annual incidence of major bleeding in trials and cohort studies has been reported to be between 1.1% and 2.3% in patients treated with warfarin to achieve an international normalized ratio (INR) of 2.0 to 3.0. The...
متن کاملEmergency reversal of anticoagulation after intracerebral hemorrhage.
BACKGROUND AND PURPOSE Although intracerebral hemorrhage is one of the most serious complications during oral anticoagulant therapy, there are no guidelines on emergency treatment with respect to reversal of anticoagulation effect in these patients. METHODS We retrospectively compared laboratory data and clinical features in 17 cases of anticoagulant-related intracerebral hemorrhage treated w...
متن کاملLow-dose vitamin K to augment anticoagulation control.
STUDY OBJECTIVES To determine the effect of daily low-dose oral vitamin K supplementation on reducing variations in the international normalized ratios (INRs) in patients taking warfarin. DESIGN Retrospective analysis. SETTING Anticoagulation clinic in a large, private-practice hematology group. PATIENTS Eight motivated patients (three men, five women), aged 45-79 years, receiving anticoa...
متن کاملCase scenario: emergency reversal of oral anticoagulation.
REVERSING warfarin-induced anticoagulation quickly and effectively can be challenging in medically compromised patients presenting for emergency surgery. Anticoagulation reversal poses a delicate balance between increasing the risk of clotting and decreasing the risk of intraoperative blood loss. Furthermore, variable individual responses and warfarin’s adverse effect profile render particular ...
متن کاملQuestionable reversal of anticoagulation in the therapeutic management of cerebral haemorrhage associated with vitamin K antagonists.
Reversal of anticoagulation is recommended to correct the international normalised ratio (INR) for patients with intracranial haemorrhage (ICH) associated with vitamin K antagonists (VKA). However, the validity of such treatment is debated. We sought to identify, prospectively, the prognostic effect of VKA-ICH treatment in a cohort of patients (n=71; median age 78 years, range 20-89; 52% males)...
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ژورنال
عنوان ژورنال: Canadian Medical Association Journal
سال: 2011
ISSN: 0820-3946,1488-2329
DOI: 10.1503/cmaj.111-2011